Pericardial adipose tissue regulates granulopoiesis
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چکیده
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OBJECTIVE Macrophage recruitment to adipose tissue is a reproducible feature of obesity. However, the events that result in chemokine production and macrophage recruitment to adipose tissue during states of energetic excess are not clear. Sirtuin 1 (SirT1) is an essential nutrient-sensing histone deacetylase, which is increased by caloric restriction and reduced by overfeeding. We discovered th...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2018
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2018.27